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Description :
G-quadruplex motifs in the promoters of human, chimpanzee, rat, mouse and bacterial genes


Description :
Sequences and properties of Piwi-interacting RNAs (piRNAs) in human, mouse and rat

Mammalian Gene Collection

Description :
The NIH Mammalian Gene Collection (MGC) program is a multi-institutional effort to identify and sequence cDNA clones containing a full-length open reading frame (FL-ORF) for human, mouse, and rat genes. To date, the MGC has produced over 324 cDNA libraries derived from human tissue and cell lines, as well as mouse and rat tissues. The MGC has sequenced and verified the complete FL-ORFs for a non-redundant set of 11,666 human, 10,602 mouse, and 854 rat genes.

5' expressed-sequence tags (ESTs) are generated from libraries and analyzed to identify candidate complete ORF clones. These clones are subjected to high accuracy full-insert sequencing and assessed for complete ORFs. Candidate clones for genes are clones that have been identified as potential complete ORFs and are waiting full-insert sequencing. All MGC sequences are deposited in GenBank and available without restriction. The cDNA clones generated by the MGC are available through the IMAGE clone distribution network and are fully accessible to the community.

References :
Strausberg RL, Feingold EA, Klausner RD, Collins FS. The Mammalian Gene Collection. Science, 1999, 286, 455-457.

MGC (Mammalian Gene Collection) Program Team, Generation and Initial Analysis of more than 15,000 Full-Length Human and Mouse cDNA Sequences. PNAS, 2002, 99(26), 16899-16903.

iCE - internet Contig Explorer

Description :
Viewer for physical map data (for mouse, rat, cow, Cryptococcus); developed at the Genome Sciences Centre, Vancouver.


Description :
ENDEAVOUR is a computational approach to prioritizing candidate genes for further study. Users input training genes already known to be involved in the process under study and the candidate genes to prioritize. The web server now supports multiple species (i.e. human, rat, mouse) and makes use of data from various databases (i.e. ontologies, annotations, protein-protein interactions, text mining data) to generate the prioritization.

Ensembl Rat Genome Browser

Description :
The Rat Genome project is an international collaboration to sequence the genome of the brown rat (Rattus norvegicus).

UCSC Rat Genome Browser Gateway

Description :
Provides a rapid and reliable display of any requested portion of the rat genome at any scale, together with dozens of aligned annotation tracks.

Whole Mouse Catalog

Description :
Numerous links to Internet resources for mouse and rat research; resource categories include genome, cell, organ, organism, laboratory etc.

Rat BAC Physical Map

Description :
BAC fingerprint map of the rat genome, by Genome Sciences Centre, Vancouver.

Rat BAC Ends

Description :
TIGR BAC end sequencing project; query genomic sequence or clone name against database of BAC end sequences to find set of minimally overlapping clones; BACs are same as those fingerprinted by Genome Sciences Centre, Vancouver.

Rat Genome Database (RGD)

Description :
The Rat Genome Database (RGD) is a repository of rat genetic and genomic data. As well as integrating this data with mapping, physiological and strain information, RGD also provides researchers with several tools that facilitate searching, data mining and data analysis.

Primer Z

Description :
Primer Z is an interface for PCR primer design for human, mouse, or rat genes and human SNPs; uses Primer3 primer design program.

IPI - International Protein Index

Description :
IPI provides a top level view of the human, mouse and rat proteome data found in Swiss-Prot, TrEMBL, RefSeq and Ensembl.


Description :
The Berkeley Genome Pipeline a.k.a. Godzilla, provides precomputed VISTA plots of sequence conservation between pairs of human, mouse or rat genomes.

Gene Aging Nexus

Description :
Gene Aging Nexus (GAN, is a data mining platform for the biogerontological-geriatric research community. It enables users to analyze, query, and visualize the aging-related genomic data. Our goal is to facilitate the digestion and usage of the public genomic data. A current focus is on integrative analysis of microarray gene expression data. We are establishing a central database for aging microarray data of six species: human (H. sapiens), rat (R. norvegicus), mouse (M. musculus), fruit fly (D. melanogaster), worm (C. elegans), and yeast (S. cerevisiae). GAN is equipped with a set of bioinformatics tools for analysis of the microarray data sets, cross-platform and cross-species.

Aknowledgement :
The work was supported by a pilot grant from the Seaver foundation, the NIH Grants R01GM074163, P50HG002790, P01AG14751, R01AG13499, and the NSF grant 0515936