The GOLD.db (Genomics of Lipid-Associated Disorders Database) was developed to address the need for integrating disparate information on the function and properties of genes and their protein products that are particularly relevant to the biology, diagnosis management, treatment, and prevention of lipid-associated disorders. The database provides a reference for pathways and information about the relevant genes and proteins in an efficiently organized way. The main focus was to provide biological pathways with image maps and visual pathway information for lipid metabolism and obesity-related research. For each element in the pathway, specific information exists including structured information about a gene, protein, 3D-structure, gene regulation, function, literature, and links. Currently, the insulin signaling and the adipogenesis pathways are available. Additionally, analytic and data mining tools, reagents, protocols, videos, references, and links to relevant genomic resources were included in the database. GOLD.db is available at http://gold.tugraz.at.
This work was supported by the Austrian Science Fund, Project SFB Biomembranes F718. Diego Miranda-Saavedra was supported by an EU Marie Curie Training Site program “Genomics of Lipid Metabolism”.