The Candida Genome Database (CGD; http://www.candidagenome.org) is a resource for information about the genomic sequence and molecular biology of the fungal pathogen Candida albicans.
CGD collects and organizes data from the biological literature concerning C. albicans, and provides curated gene product descriptions, Gene Ontology annotation, mutant phenotypes, and gene-specific reference lists. CGD also provides tools for viewing, browsing, and downloading C. albicans sequence data from the most recent genome sequence assembly as well as from multiple previous assemblies.
CGD also provides curated pathway information, with the ability to browse metabolic pathways using the Pathway Tools software from SRI.
CGD contains additional online resources for the C. albicans research community, including a gene name registry, laboratory contact information, research job opportunities, and research community news. CGD welcomes comments and suggestions; to contact CGD curators, please email firstname.lastname@example.org.
CGD is supported by NIH grant R01 DE015873 from the NIDCR at the NIH.
CandidaDB is a database dedicated to the genome of the most prevalent systemic fungal pathogen of humans, Candida albicans. CandidaDB Release 2.0 (June 2004) contains information pertaining to Assembly 19 of the genome of C. albicans strain SC5314. The current release contains 6244 annotated entries corresponding to 130 tRNA genes and 5917 protein-coding genes. For these, it provides tentative functional assignments along with numerous pre-run analyses that can assist the researcher in the evaluation of gene function for the purpose of specific or large-scale analysis. CandidaDB is based on GenoList, a generic relational data schema and a World Wide Web interface that has been adapted to the handling of eukaryotic genomes. The interface allows users to easily browse through genome data and retrieve information. CandidaDB also provides more elaborate tools, such as pattern searching, that are tightly connected to the overall browsing system. Because the C. albicans genome is diploid and still incompletely assembled, CandidaDB provides tools to browse the genome by individual supercontigs and to examine information about allelic sequences obtained from complementary contigs.
Sequence data from C. albicans were obtained from the Stanford Genome Technology Center. Sequencing of C. albicans was accomplished with the support of the NIDR and the Burroughs Wellcome Fund. This work was supported by grants from the European Commission (QLK2-2000-00795; MCRTN-CT-2003-504148 ; 'Galar Fungail Consortium’) to AJPB, CE, AD, JE, CG, BH, FMK, JPM and RS and the Ministère de la Recherche et de la Technologie (P.R.F.M.M.I.P. 'Réseau Infections Fongiques’) to CE and CG.